fosaprepitant will raise the amount or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
istradefylline will boost the stage or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
apalutamide will lower the extent or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a strong CYP3A4 inducer, with drugs that are CYP3A4 substrates may end up in reduced publicity to those remedies.
Limit dosages and durations towards the minimum essential. Stick to people for symptoms and signs and symptoms of respiratory depression and sedation.
Watch Carefully (one)oxcarbazepine will lower the extent or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
metronidazole will improve the amount or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
VALTOCO® (diazepam nasal spray) is a direct-use seizure medication utilised to deal with episodes of Regular seizures in adults and children six a long time and more mature. VALTOCO won't exchange each day anti-seizure drugs and may be utilized only as desired.
butabarbital will decrease the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Throw absent (discard) the made use get more info of VALTOCO. If needed, a next dose could be presented no less than four hrs after the initial dose, utilizing a new pack of VALTOCO. Will not give greater than 2 doses of VALTOCO to deal with a seizure cluster. A second dose really should not be specified when there is problem about the person’s respiratory, they need help with their respiration, or have Serious drowsiness.
environmentally friendly tea decreases consequences of diazepam by pharmacodynamic antagonism. Minimal/Significance Unidentified. Caffeine ingredient of eco-friendly tea may perhaps reduce sedative effects of benzodiazepines.
buprenorphine transdermal and diazepam the two improve sedation. Avoid or Use Alternate Drug. Restrict use to clients for whom option procedure solutions are insufficient
Check Closely (one)enasidenib will enhance the stage or influence of diazepam by impacting hepatic enzyme CYP2C19 metabolism.
VALTOCO may make you sleepy or dizzy and might gradual your imagining and motor skills. Tend not to travel, operate large equipment, or do other unsafe routines until eventually you know the way VALTOCO impacts you.
ribociclib will raise the degree or outcome of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.